"In the laboratory, caffeine has been found to both enlarge hair follicles and lengthen their growth phase."

When it’s used for hair loss, caffeine is given as a topical treatment (most commonly, it’s included in a shampoo).

"The beneficial effects of topical application of caffeine in AGA"

can thus be attributed to inhibition of phosphodiesterase, improvement in barrier function, follicular penetration, stimulation and promotion of hair growth.